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Moreover, a study involving 214 pregnant women determined that those with UIC between 250-499 g/L exhibited higher rates of GDM (20.3%) compared to the group with UIC 150-249 g/L (9.7%) (86)

The extended chain means more potential points for degradation

For instance, despite its excellent mucus penetration, PDA may induce cytotoxicity or disrupt gut microbiota homeostasis and bile acid metabolism if unpolymerized monomers remain or high doses are used (Qian et al., 2022)