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Combining glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) in patients with type 2 diabetes mellitus (T2DM)

S10 is most common during active treatment at therapeutic doses (1.01.7mg)

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Emerging evidence suggests that GLP-1 treatment in mice may also require an intact leptin pathway, since ob/ob or db/db mice are mostly refractory to weight loss