melanotic macule on lip Spot the Dot! Growths the lips are not too common. Clinically, this Melanotic macule. Benign. Dark spot

The Study: How Glutathione Deficiency Ties into Type 2 Diabetes Researchers conducted a case-control study to explore whether patients with type 2 diabetes, particularly those with microvascular complications, have lower levels of GSH compared to healthy individuals

It is the predominant intracellular non-protein thiol in mammalian tissues, present at concentrations typically ranging from 110 mM in the cytosol, with particularly high concentrations in the liver (up to 10 mM), which is the primary site of GSH synthesis and export

One exception is fluids lining the lower part of the respiratory tract, where it may help to scavenge inhaled toxins and free radicals produced by activated lung phagocytes

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