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Although these medications serve different purposes, understanding their uses, benefits, and risks can be beneficial for both patients and healthcare providers

Adults with type 2 diabetes were eligible for the industry-sponsored FLOW (Evaluate Renal Function with Semaglutide Once Weekly) trial if they had high-risk kidney disease and were receiving a stable maximal dose of renin-angiotensin system (RAS) inhibitors

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Safety Considerations and Dose Adjustments Semaglutide at any dose requires baseline kidney function assessment and periodic monitoring, especially as doses increase toward 2.4 mg or higher