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Approximately 50% of participants achieved at least 20% weight reduction, representing weight loss magnitudes that overlap with those seen in some bariatric surgery studies, though long-term durability and effects on comorbidities may differ

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The effect of very-low-calorie diet on mRNA expression of inflammation-related genes in subcutaneous adipose tissue and peripheral monocytes of obese patients with type 2 diabetes mellitus

Momen Razmgah M, Ghahremanloo A, Javid H, AlAlikhan A, Afshari AR, Hashemy SI (2022) The effect of substance P and its specific antagonist (aprepitant) on the expression of MMP-2, MMP-9, VEGF, and VEGFR in ovarian cancer cells