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The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events (heart attack, stroke, cardiovascular death) in people with obesity and established cardiovascular disease

Other anomalies observed include visual defects (63%), cardiac defects (51%), constipation (51%), frequent infections (47%), behavioural problems (39%), sleep disturbances (37%), and microcephaly (31%) (Kennedy et al, 2019)

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Key Words: Anti-tuberculosis drugs, Hepatotoxicity, Acetyl-L-carnitine, Alpha-lipoic acid, Coenzyme Q10 Introduction Tuberculosis (TB) is an important health problem in the world that is one of the top 10 causes of death