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Moreover, alterations in the activity or concentration of cystathionine -synthase and cystathionine -lyase have been associated with various pathological conditions and diseases, including diabetes, cancer, AIDS, neurodegenerative disorders, and liver diseases [29, 30, 31]
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MGF is framed as a local, autocrine/paracrine signal: it is produced within loaded muscle, acts on nearby cells, and is transient, with expression peaking early after injury and declining within days
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