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3 (download XLSX Source data for Extended Data Fig

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In the coming years, several trends are likely to emerge: Rapid growth in the number of oral GLP-1 drugs Small-molecule GLP-1 therapies becoming a major R&D focus Manufacturing capacity becoming a key competitive factor Continued entry of emerging biotechnology companies into the sector At the same time, dual-target GLP-1 drugs , GLP-1/GIP co-agonists , and oral multi-target metabolic therapies are also advancing rapidly