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Moringa root extract significantly reduced TGF--induced phosphorylation of ERK and suppressed SMAD4 expression in rat kidney fibroblast cells, suggesting its potential to attenuate renal fibrosis

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Subsequently, blood samples were collected to evaluate the pharmacokinetic parameters using high-performance liquid chromatography, and it was found that QUE significantly increased the plasma concentration of 5-FU and improved the availability of 5-FU (43)