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Storage plays crucial part in maintaining efficacy, stability and sterility of drug product

It has been investigated for its involvement in angiogenic signaling , where it is referenced in the literature as a modulator of vascular growth factor pathways

An additional recognized factor of unfavorable response to classic pharmacological treatment is AIP or MEN-1 germline mutated status

Prerequisites for First-in-Human Clinical Trials A FIH trial must meet the following prerequisites: Data on the Quality of the Investigated Drug The quality of the administered pharmaceutical formulation should be extensively evaluated before initiating the clinical trial