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However, the clinical significance of the observed changes in insulin and glucose levels needs to be assessed in longer-term studies

The interaction of active GLP-1R with VAPB was deemed functionally relevant, as it was no longer present when VAPB P56S, a self-aggregating loss-of-function VAPB mutant associated with amyotrophic lateral sclerosis (ALS) 16,17 , was expressed instead of its wildtype (WT) counterpart (Supplementary Fig

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

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