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(b) The role of metabolic reprogramming in ferroptosis, analyzing how lipid, amino acid, iron, and glucose metabolism are reshaped or disrupted in OA, thereby influencing the occurrence and progression of ferroptosis

ACTL6A knockdown (KD) via short hairpin RNA (shRNA) transfection exerted a marked negative effect on GC cell proliferation, while overexpression of ACTL6A exerted a positive effect on GC cell proliferation (Fig

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