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Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD with transfusions changing to hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

FDA explains that compounded drugs are not FDA-approved in the same way as approved medicines, and unapproved drugs may lack evidence of safety, effectiveness, quality, and labeling adequacy [16] 17

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Depending on the surface area of the burn, burns are classified as mild, moderate, or severe