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For example, Nrf2, a representative antioxidant gene, activates the transcription of ferritin heavy chain 1 (a protein involved in iron storage) and heme oxygenase-1 (a protein involved in heme breakdown) to reduce labile iron and regulate iron metabolism and oxidative stress [15,45]

In support, clinical data show that children with ADHD have an estimated 1.3-fold increase in mtDNA copy number compared to neurotypical controls [97], which may reflect a compensatory response to mitochondrial dysfunction

Recent research also examines BPC-157's potential role in metabolic health

The effects of redox controls mediated by glutathione peroxidases on root architecture in Arabidopsis thaliana