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While proline mimetics have been shown to inhibit DPP-4, an unexpected finding in this study was that piperidine-3-carboxylic acid exhibited five-fold greater efficacy than the compound derived from L-proline

Prandial options to advance basal insulin glargine therapy: testing lixisenatide plus basal insulin versus insulin glulisine either as basal-plus or basal-bolus in type 2 diabetes: the GetGoal Duo-2 trial

47 Importantly, a direct comparison was made between the degree of weight loss and change in MDS UPDRS part 3 OFF scores and revealed no correlation between these two parameters, and the primary analysis result remained statistically significant when adjusted for the degree of weight loss

For example, oral semaglutide uses a specialized absorption enhancer to allow uptake in the stomach