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Victoza provided significant A1C reductions over 26 weeks for adult patients with type 2 diabetes and moderate renal impairment 6,c Primary endpoint: Average A1C reductions Baseline A1C 8.0% to 8.1% c Mild renal impairment=eGFR 60 to 89 mL/min/1.73 m 2
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It is likely that the balance between glutamate and GABA may determine the excitatory/inhibitory balance in the central nervous system and hence the ratio of signal to noise
