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In animal models of HF, GLP-1R agonists increase myocardial glucose uptake [62], stroke volume and LVEF, accompanied by decreasing LVEDP and systemic vascular resistance [63]

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Caffarelli, Glucagon-like Peptide-1 receptor agonists and diabetic osteopathy: another positive effect of incretines

The impact of the gut microbiota on host amino acid metabolism can further influence disease progression and therapeutic response [80]