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In the Phase III BALATON and COMINO studies, treatment with Vabysmo led to early and sustained improvement in vision in people with branch and central RVO, Genentech reported, which met the primary endpoint of non-inferior visual acuity gains at 24 weeks compared to Regenerons Eylea (aflibercept)

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Instead, it works by inhibiting NNMT, which helps preserve NAD+ levels and enhances cellular metabolism, particularly in fat cells

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doi: 10.1016/j.envint.2024.109032 82 TakalaniNBMonagengEMMohlalaKMonseesTKHenkelROpuwariCS

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