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For instance, it has been recently observed that in prostate cancer patients, polymorphism in GSTM3-3 may contribute to resistance to hormonal therapy through oxidative stress 45

doi: 10.1111/imr.12624 191

Overdose symptoms are severe, prolonged, and disablingintense vomiting, incapacitating abdominal pain, and symptoms that worsen rather than improve over 24-48 hours signal overdose and require medical evaluation