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In one randomized controlled trial that included 60 participants with a BMI of 35 or higher and type 2 diabetes for 5 years, 75% of those who underwent gastric bypass surgery and 95% of those who underwent a type of metabolic surgery known as biliopancreatic diversion were diabetes-free two years later, but no one treated with non-surgical interventions alone experienced diabetes remission (Mingrone 2012)

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The Future of GLP-1 Patches: Current Limitations in 2026 Several pharmaceutical companies have invested in GLP-1 patch technology, but clinical adoption remains limited