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bioRxiv2024 May 1

Fulminant hepatic failure in rats: survival and effect on blood chemistry and liver regeneration

That trial also reported transient, mild lower-extremity edema and muscle pain, a body-weight increase of about 2.7 kg in the MK-677 group versus 0.8 kg on placebo, an average rise in fasting glucose (about 5 mg/dL), and a measurable decrease in insulin sensitivity

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