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Injection site reactions usually clear within 24 to 48 hours

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Its receptor, glucagon-like peptide-1 receptor (GLP-1R), is expressed not only in metabolic centers like the hypothalamus but also in reward-related brain regions, including the ventral tegmental area (VTA), nucleus accumbens (NAc), and prefrontal cortex (PFC) [8,9,10]

A Comprehensive Look at Its Benefits and Bioavailability explains why that matters