Leakage: If the rubber stopper is damaged or there is liquid dried around the rim, the sterility of the vial may be compromised
More broadly, side effects follow a predictable pattern of being most prominent during the first 4-8 weeks of therapy and during each dose escalation
For example: Fatigue, unexplained weight loss, or abdominal pain may indicate liver disease or cancer Easy bruising, night sweats, or feeling full quickly (early satiety) may suggest a myeloproliferative disorder Swelling in the legs, reduced urine output, or persistent nausea may point to kidney disease In cases of very high B12 from injections (not oral supplements), some people have reported headache, nausea, diarrhea, facial flushing, or skin rash
Focus: Progressive overload