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In the SURPASS clinical trial program, tirzepatide reduced HbA1c by 2.0-2.4% depending on dose, bringing the majority of participants to target levels below 7.0%

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To avoid these limitations, targeted activation of the endogenous cellular antioxidant machinery has emerged as an alternative therapeutic strategy for the reduction of oxidative stress (Davis and Pennypacker 2017

Wegovy pills and pens are similar in effectiveness and cost but have different FDA approvals