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Key Takeaways Semaglutide reduces emotional eating by suppressing appetite and curbing cravings for hyperpalatable foods within the first few weeks of treatment

Tirzepatide may cause slightly more headaches initially due to its dual receptor activation affecting both GLP-1 and GIP pathways in the brain simultaneously, though the data does not show a statistically significant difference between the two medications

Patients experiencing nausea, vomiting, or diarrheacommon side effects, especially during dose initiation or escalationmay inadvertently decrease their consumption of both food and beverages while experiencing increased fluid losses, resulting in dehydration that manifests as oral dryness