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As also observed in the repeat experiment of Cagri-CTR-Gs, due the smaller dataset and lower resolution imaging, 25% of the particles could not be classified due to poor resolution features in the ECD (Supplementary Fig

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To prevent this, most multi-dose aqueous nasal sprays contain antimicrobial preservatives (most commonly benzalkonium chloride at 0.010.02% w/v, often combined with EDTA as a chelating agent)