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Time from randomization to first cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke was analyzed using a Cox proportional hazards model with treatment as categorical fixed factor

By blocking the action of glucagon, GRAs aim to lower blood glucose levels, especially in individuals with type 2 diabetes or MetS characterized by IR and dysregulated glucose metabolism (303)

Persistent nausea, vomiting, or severe constipation that does not resolve after several months may prompt a switch to the single-mechanism semaglutide

Hence, the anti-arrhythmic effects of semaglutide must be considered in the relevant clinical context i.e., in T2DM patient with MI