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Consequently, ulcers may persist longer, recur more frequently, and cause greater discomfort in B12-deficient individuals compared to those with adequate nutritional status

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This approach reflects a broader shift in heart care, treating multiple risk factors together, earlier, rather than waiting for a heart event to occur

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Importantly, carnosine was consistently downregulated in both pneumonia models as it is mechanistically linked to histidine and thiamine metabolism (Figures 2F, G), which suggests that carnosine may serve as a critical pneumonia-associated metabolite

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