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Wang, M., Firrman, J., Zhang, L., Arango-Argoty, G., Tomasula, P., Liu, L., Xiao, W., & Yam, K

Compounding pharmacies operate under different and generally less stringent standards

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In addition, novel regulators such as RNA methylation enzymes (METTL3/14) that modulate GPX4 mRNA stability (176), or RhoA-mediated vascular remodeling that enhances iron leakage into subchondral bone ( Future research should leverage high-resolution single-cell or spatial omics, functional validation in cell-specific knockout models, and joint-region-targeted delivery systems to develop more personalized and mechanistically guided ferroptosis interventions