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Fu, Qiang

Mucolytics such as dornase alfa (NCT04402944, phase II of recombinant human DNase I for COVID-19) and mannitol (NCT00251056, phase II of mannitol for cystic fibrosis) have been tested mainly to relieve mucus blockages, but they do not assist drugs breakthrough or controllability interact with the mucus effectively

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The results of an in vitro model revealed that sulforaphane enhances the activation of Nrf2 signaling in normal mucosal epithelial cells and head and neck squamous cell carcinoma cell lines