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Conversely, IGF-1 receptors are also widely expressed but exhibit higher densities in the cortex, hippocampus, and thalamus, with moderate expression in the olfactory bulb, hypothalamus, and cerebellum [95]

As a matter of fact, treatment with bromocriptine and other DA drugs generally is considered as symptomatic since DA discontinuation often leads to recurrence of hyperprolactinemia and to tumor regrowth in most patients at least after short-term use