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For people who cannot absorb B 12 , the condition cannot be prevented

Its half-life is also relatively short, measured in minutes to a few hours, necessitating frequent administration in research protocols to elicit its effects on insulin sensitivity and cellular energy

However, two other forms hydroxocobalamin and cyanocobalamin become biologically active after they are converted to methylcobalamin or 5-deoxy adenosylcobalamin, said Dr Aravinda G M, consultant, internal medicine, Manipal Hospital, Jayanagar, Bangalore

When enough electrons are lost without prompt replacement, this process of oxidation eventually results in cellular, and ultimately tissue, damage