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This article explains what Lemon Bottle claims to do, why many clinicians have concerns, what regulation looks like in the UK, what side effects to watch for, and what safer, evidence-based options exist for submental fat (double chin) and stubborn body fat

First, in gain-of-function experiments, we examined whether overexpression of secreted, catalytically active LOXL2 increases BHZ incorporation in vascular smooth muscle cells (VSMCs)