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The diminishing returns after week 6 don't justify the extended suppression of endogenous IGF-1 axis function or the longer washout required (1012 weeks instead of 68) to restore baseline receptor density

The study of about 7,000 children between ages 12 and 18, published this week in the journal JAMA Pediatrics, showed that the medicines were associated with a 33% lower risk over a year

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Phase III: Elimination The final phase involves transporting these now-water-soluble complexes out of the cells and into the bile or urine for final elimination