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For example, hepatocyte growth factor (HGF) secreted by dermal white adipose tissue activates the Wnt/-catenin signalling pathway and enhances the pigmentation of hair follicles by upregulating the expression of AXIN2, LEF-1, Wnt10b, and Wnt6

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262 Potential role of -catenin as a diagnostic biomarker in non-tumour diseases TGase-1 is a keratinocyte differentiation marker related to the differentiation of keratinocytes, and its expression increases in psoriatic skin