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The guideline advances a new approach to risk assessment through a novel risk score, sets lower low-density lipoprotein cholesterol (LDL-C) and nonhigh-density lipoprotein cholesterol (HDL-C) treatment goals for patients with established atherosclerotic cardiovascular disease (ASCVD), and recommends measuring lipoprotein(a) [Lp(a)] at least once to identify individuals at higher risk of ASCVD.The guideline dissemination tools include a Central Illustration to graphically convey key concepts, as well as tables highlighting updates in the ACC/AHA/Multisociety Dyslipidemia Guideline and comparisons to the 2025 European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) Focused Update of the 2019 Guidelines for the Management of Dyslipidaemias

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doi: 10.3389/fendo.2023.1095753 Received 11 November 2022 Accepted 08 February 2023 Published 22 February 2023 Volume 14 - 2023 Edited by Xiaodong Sun, Affiliated Hospital of Weifang Medical University, China Reviewed by Raffaele Carraro, La Princesa University Hospital, Spain