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Similarly, regional initiatives like the European Green Deal and Sustainable Energy Action Plans (SEAPs) aim to decarbonize urban areas through integrated approaches, including Zero Energy Buildings (ZEBs), Net-Zero Energy Districts (NZEDs), and Positive Energy Districts (PEDs) (Sassenou et al., 2024)

Indeed, Ng FolEIB, as purified, features additional electron density on the nonliganding cysteines, C149 (Figure 30B) assigned as an S -nitrosated Cys essentially positioned on top of the active site

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This stabilizes the transcription factor BACH1, which subsequently upregulates angiogenesis-related factors, including PDGFB, EGFR, FGF2, and FGFR1, ultimately driving vascular regeneration