Practical Application Start with protein and vegetables: Activates L-cells early, triggers initial GLP-1 release Add healthy fats: Sustains L-cell activation, slows gastric emptying Include complex carbohydrates: Provides sustained nutrient flow to L-cells Finish with fruit (optional): Final fiber and polyphenol boost Protein source: 25-30 grams (palm-sized portion) Non-starchy vegetables: 2-3 cups (fiber and volume) Healthy fat: 1-2 tablespoons olive oil or avocado Complex carbohydrate: -1 cup quinoa, sweet potato, or legumes Example L-Cell Optimizing Meals: Breakfast: Greek yogurt with berries, ground flaxseed, chopped walnuts, and a drizzle of honey Lunch: Grilled chicken over mixed greens with chickpeas, avocado, and olive oil dressing Dinner: Baked salmon with roasted Brussels sprouts and quinoa, side of sauerkraut Advanced Strategy: Time-Restricted Feeding The Science: L-cells demonstrate circadian rhythms in their GLP-1 secretion capacity
J.HalperinM
Conversely, animals administered either GLP-1 or GLP-1MK-801 exhibited diminished locomotion compared with both MK-801-treated and vehicle-treated mice
When you eat a meal, GLP-1 medications tell your body to make more insulin and slow down digestion, which makes you feel full longer and signals to your brain that youre full, says Dr