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The Study of Tirzepatide (LY3298176) in Participants With Obesity (SURMOUNT-1) trial found that tirzepatide at 15 mg per week taken over 72 weeks reduced body weight by 20.9% in those with obesity but without diabetes [9]
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Conversely, selective loss of adipocyte DPP-4 enhances hepatic insulin sensitivity and reduces inflammation, with no effects on glucose tolerance [4]
Effectiveness and safety of adalimumab in patients with ankylosing spondylitis or psoriatic arthritis and history of anti-tumor necrosis factor therapy
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