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Experimental evidence suggests Glutathione may have a modulatory or protective role, warranting further investigation.Thiol-antioxidants such as glutathione can modulate EBV infection by altering the redox state of cell surface proteins, including the CD21 receptor, which is essential for EBV entry into B cells
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In Arabidopsis, arGST loss-of-function mutations were additionally linked with an increased content of flavonols 19,45 , most probably due to a second oxidation of accumulating flavan-3,3,4-triol ( 4 ), which is catalysed by At LDOX in vitro 11,12,13
Whilst we found that ex vivo vehicle treated cells produced high levels of cytokines, including IL-5, IL-13, IL-9 ( Supplementary Figures 4BD ), and modest amounts of IL-10 and IL-6 ( Supplementary Figures 4E, F ), melatonin treatment greatly reduced the concentration of all cytokines analyzed ( Supplementary Figures 4B F )
