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GLP-1 drugs slow gastric emptying and may alter lipid handling, requiring baseline assessment

This drug must be taken while fasting with specific intake instructions to optimize uptake, whereas orforglipron does not require fasting or enhancer co-administration

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Laser-induced microvascular endothelial damage results in rapid platelet adhesion to the denuded surface and to each other, with minimal entrapment of erythrocytes