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These insights may help provide context for understanding your baseline metabolic characteristics and potential responsiveness to GLP-1 therapy, though genetic predisposition does not predict exact medication response and should be interpreted with a qualified healthcare provider

2013;8:e76786

Indeed, the pharmacokinetic and pharmacodynamics of any drug taken by mouth should be appraised considering the role of the microbiota, as the varied efficacy of some chemotherapeutics such as 5-FU has been proven to directly depend on this host-microbiota metabolism (400)