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Although the exact composition of these multi-molecule complexes depends on the activator, they classically comprise a NOD-like receptor (NLR) that acts as a sensor, such as NLRP3 and NLRP1, the adaptor protein apoptosis-associated speck-like protein containing a CARD (ASC, also referred to as PYCARD) and the catalytic protein caspase 1 (CASP1) [8]

The rats were randomized into an experimental treatment group and a control group that were intramuscularly injected with 10 ug/kg of cortagen or a saline solution, respectively, daily over 10 days

Jansen N

Ferroptosis role in complexity of cell death: unrevealing mechanisms in Parkinsons disease and therapeutic approaches