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Storage & Handling Store at controlled room temperature (typically 1525C) Keep sealed and protected from contamination Use aseptic techniques when handling Discard if solution becomes discoloured or particulate matter is present For multi-use applications, follow appropriate laboratory protocols For research use only

Many patients choose the compounded route specifically because the predictable cash price is lower than the branded copay over a year of treatment

In a statement, the FDA commissioner, Martin Makary, said the drug would now be approved for patients with cerebral folate deficiency (CFD), a condition sometimes associated with autism spectrum disorders

28 Bertoglio, K., Jill James, S., Deprey, L., Brule, N