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Microangiopathic hemolytic anemia is most commonly seen with disseminated intravascular coagulation (DIC), but it also occurs in thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), malignant hypertension, systemic lupus erythematosus, and disseminated cancer

The HepG2 cell line was gifted by Xianghua Yans lab (Huazhong Agricultural University)

The hematologic consequences of diminished synthesis of one globin chain stem not only from hemoglobin deficiency but also from a relative excess of the other globin chain, particularly in -thalassemia (described later)

10.1681/ASN.2021050680 115 VeselyO.BaldovskaS.KolesarovaA