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However, in case of the ASCT2, studies showed that cysteine is actually a competitive inhibitor and not a substrate for ASCT2 (19, 20)

However, these cardiovascular applications require particularly careful consideration given the potential risks associated with promoting angiogenesis in patients who may have undiagnosed malignancies or other conditions where angiogenesis promotion could be detrimental

However, compounded medications carry additional unknowns because different compounding pharmacies may use different formulations, concentrations, and inactive components

According to the protein misfolding avoidance hypothesis, natural selection disfavors the misfolding of highly expressed proteins, thereby constraining their evolution to minimize cytotoxicity 38