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Current algorithms for the use of HCV virological tools in the treatment of chronic hepatitis C, according to the HCV genotype: genotype 1 (A), genotypes 2 and 3 (B), and genotypes 4, 5 and 6 (C) The approved dose of pegylated IFN alfa-2a is 180 g per week, independent of body weight, whereas that of pegylated IFN alfa-2b is weight-adjusted at 1.5 g/kg per week, identical for all HCV genotypes

Patient adherence to dosing recommendations and lifestyle modifications can substantially impact how quickly tolerance develops and symptoms resolve

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Verma S, Bain SC, Monk Fries T, Mazer CD, Nauck MA, Pratley RE et al (2019) Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: a post hoc analysis of the LEADER and SUSTAIN 6 clinical trials