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investigated the regulatory effect of epithalon on the production of melatonin and cortisol in senescent monkeys, finding that the peptide significantly stimulated melatonin synthesis, thus normalizing the circadian rhythm of cortisol secretion [11]

Additionally, these are separately payable services when provided with an Annual Wellness Visit (AWV) and the AWV is included in the Shared Savings Program definition of primary care services for purposes of beneficiary assignment