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It was developed as a selective activator of the parathyroid hormone 1 receptor (PTH1R) with a preferential binding to the RG receptor conformation, which is associated with transient cAMP signaling

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Additionally, the gastrointestinal side effects common with GLP-1s (such as nausea, bloating, or diarrhea) can make hyperpalatable foods less appealing, creating a subtle but powerful disincentive