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Among them, protein kinase C (PKC), a family of protein kinase enzymes involved in various cellular mechanisms, has been shown to phosphorylate NRF2 at Ser40 in its Neh2 domain, disrupting the association with KEAP1 and promoting its activation [203, 204]

These results highlight the complexity of cellular responses to chemotherapeutic agents and antioxidants

The characteristic bands detected at 3328 cm 1 and 1576 cm 1 correspond to the stretching vibration of N-H bonds [26, 32]

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